Fungal Otomastoiditis caused by Aspergillus fumigatus in an immunocompromised patient: case report and literature review


  • Juan Carlos Rivas Rodríguez
  • Daniel Contreras Zamorano
  • Estrella Viridiana Enríquez García
  • Carlos Ricardo Flores Soriano
  • Alfredo Raúl Rodolfo Morayta Ramírez Corona



Aspergillus fumigatus, invasive aspergillosis, Otomastoiditis, filamentous fungi, neutropenia, triazole antifungals


This case report describes a 10-year-old male diagnosed with high-risk B-cell Acute Lymphoblastic Leukemia at a tertiary care center undergoing consolidation with the Total XV protocol. The patient, with a history of Rhino-sinusal Aspergillosis and secondary prophylaxis, presented with recurrent middle ear infections, bilateral non-purulent serous discharge, otalgia, mastoid pain, persistent high-grade fever, and profound neutropenia. Fungal ostomastoiditis was diagnosed and treated with targeted antifungals, yielding a positive response.


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How to Cite

Rodríguez, J. C. R., Zamorano, D. C., García, E. V. E., Soriano, C. R. F., & Corona, A. R. R. M. R. (2024). Fungal Otomastoiditis caused by Aspergillus fumigatus in an immunocompromised patient: case report and literature review. South Florida Journal of Development, 5(2), 448–451.

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