Fungal Otomastoiditis caused by Aspergillus fumigatus in an immunocompromised patient: case report and literature review

Authors

  • Juan Carlos Rivas Rodríguez
  • Daniel Contreras Zamorano
  • Estrella Viridiana Enríquez García
  • Carlos Ricardo Flores Soriano
  • Alfredo Raúl Rodolfo Morayta Ramírez Corona

DOI:

https://doi.org/10.46932/sfjdv5n2-003

Keywords:

Aspergillus fumigatus, invasive aspergillosis, Otomastoiditis, filamentous fungi, neutropenia, triazole antifungals

Abstract

This case report describes a 10-year-old male diagnosed with high-risk B-cell Acute Lymphoblastic Leukemia at a tertiary care center undergoing consolidation with the Total XV protocol. The patient, with a history of Rhino-sinusal Aspergillosis and secondary prophylaxis, presented with recurrent middle ear infections, bilateral non-purulent serous discharge, otalgia, mastoid pain, persistent high-grade fever, and profound neutropenia. Fungal ostomastoiditis was diagnosed and treated with targeted antifungals, yielding a positive response.

References

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- Kwon-Chung, K. J., & Sugui, J. A. (2013). Aspergillus fumigatus--what makes the species a ubiquitous human fungal pathogen?. PLoS pathogens, 9(12), e1003743.

- Ali, K., Hamed, M. A., Hassan, H., Esmail, A., and Sheneef, A. (2018). Identification of fungal pathogens in otomycosis and their drug sensitivity: our experience. Int. Arch. Otorhinolaryngol. 22, 400–403.

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Published

2024-01-24

How to Cite

Rodríguez, J. C. R., Zamorano, D. C., García, E. V. E., Soriano, C. R. F., & Corona, A. R. R. M. R. (2024). Fungal Otomastoiditis caused by Aspergillus fumigatus in an immunocompromised patient: case report and literature review. South Florida Journal of Development, 5(2), 448–451. https://doi.org/10.46932/sfjdv5n2-003

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